AI companies in Baltimore

Companies building or applying AI with documented Baltimore-area connections. Each profile distinguishes local headquarters, regional operations, and historical ties.

Maryland AI and research services firm with documented federal laboratory work in Baltimore.

b.well Connected Health

Baltimore connected-health platform offering AI navigation and interoperable patient data.

Baltimore talent and technology company using predictive AI in talent discovery.

CyberPoint International

Columbia AI strategy, model development, and MLOps through the AIZEN team.

EcoMap Technologies

Baltimore AI resource mapping and conversational navigation for local ecosystems.

AI Infrastructure

Fulton privacy-preserving software for encrypted analytics and machine learning.

Baltimore digital services with AI, data engineering, and human-reviewed automation.

Managed cybersecurity and an AI-centric security operations platform, based in Columbia.

Infinite Biomedical Technologies

Baltimore prosthetic-control company with documented machine-learning development.

Baltimore retinal-imaging AI for research; investigational use, not clinical diagnosis.

Leidos (Greater Baltimore operations)

Regional agentic AI development through Leidos company Kudu Dynamics in Columbia.

Baltimore AI consulting, custom software, copilots, and workflow automation.

Mind Over Machines

Owings Mills AI integration, business automation, and workforce adoption consulting.

PGDx, part of Labcorp

Baltimore-origin genomics business using machine learning in cancer-testing analysis.

AI application-security triage and code remediation, with a Baltimore company base.

Protenus, acquired by Bluesight

Baltimore-founded AI compliance analytics business, acquired by Bluesight in 2025.

AI for technical documentation, search, and procedural guidance.

Johns Hopkins spinout developing ultrasound and AI for dialysis-access visualization.

Columbia-based exposure management with agentic AI for cybersecurity workflows.

Columbia digital-health company with an AI Lab focused on cardiometabolic care.

Baltimore external cybersecurity company using AI analytics; privately held since 2024.